Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 7/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5133757 | 0.87 | NFE2L2 (0.40) | NR3C2GAANFE2L2SMN1; SMN2NPC1 | |
| SCHEMBL6855010 | 0.82 | L3MBTL1 (0.39) | GAANFE2L2SMN1; SMN2KCNA5NPC1 | |
| SCHEMBL15212175 | 0.80 | NFE2L2 (0.39) | NFE2L2SMN1; SMN2KCNA5NPC1RAB9A | |
| SCHEMBL27938323 | 0.79 | SMN1; SMN2 (0.40) | NFE2L2SMN1; SMN2KCNA5NPC1RAB9A | |
| SCHEMBL7912706 | 0.76 | KIF11 (0.41) | NFE2L2SMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL7541639 | 0.76 | KIF11 (0.40) | NFE2L2SMN1; SMN2NPC1RAB9AHIF1A | |
| SCHEMBL27926604 | 0.75 | NFE2L2 (0.44) | GAANFE2L2SMN1; SMN2KCNA5ABCB1 | |
| SCHEMBL11480225 | 0.75 | SMN1; SMN2 (0.44) | GAANFE2L2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL15212075 | 0.74 | CNR1 (0.35) | GAANFE2L2SMN1; SMN2KCNA5NPC1 | |
| SCHEMBL15212062 | 0.74 | KIF11 (0.40) | NR3C2NFE2L2SMN1; SMN2KCNA5NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6379931-B1 | Chimeric DNA/RNA ribozymes containing propanediol | CITY OF HOPE | 2002-04-30 | — | — | US | disclosed |