Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7912698 | 0.87 | KIF11 (0.45) | KIF11AGTR1LMNACYP1A2SMN1; SMN2 | |
| SCHEMBL5133757 | 0.82 | NFE2L2 (0.40) | NPC1RAB9ALMNANFE2L2SMN1; SMN2 | |
| SCHEMBL1263157 | 0.81 | KIF11 (0.41) | KIF11NPC1RAB9AAGTR1LMNA | |
| SCHEMBL6855010 | 0.80 | L3MBTL1 (0.39) | KIF11NPC1RAB9ALMNANFE2L2 | |
| SCHEMBL15517408 | 0.77 | AGTR1 (0.38) | KIF11NPC1RAB9AAGTR1LMNA | |
| SCHEMBL27938323 | 0.76 | SMN1; SMN2 (0.40) | KIF11NPC1RAB9ALMNACYP1A2 | |
| SCHEMBL7646522 | 0.76 | NR3C2 (0.38) | NPC1RAB9ALMNANFE2L2SMN1; SMN2 | |
| SCHEMBL7541639 | 0.76 | KIF11 (0.40) | KIF11NPC1RAB9ANFE2L2SMN1; SMN2 | |
| SCHEMBL2686112 | 0.75 | KIF11 (0.64) | KIF11LMNASMN1; SMN2HTTKCNH2 | |
| SCHEMBL15212175 | 0.75 | NFE2L2 (0.39) | KIF11NPC1RAB9ANFE2L2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187913-B1 | Covalently crosslinked oligonucleotides, preparation method and synthon which is of use in the method | GENSET (FR) | 2001-02-13 | — | — | US | disclosed |