SCHEMBL7647206

SCHEMBL7647206

CCOP(=O)(OCC)c1cc2cc(S(=O)(=O)NC(=O)c3ccccc3)c(Cl)cc2[nH]c1=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 2/20 0.41
GRIN3B O60391 2/20 0.41
GRIA1 P42261 2/20 0.41
GRIA2 P42262 2/20 0.41
GRIA3 P42263 2/20 0.41
GRIA4 P48058 2/20 0.41
GRIN1 Q05586 2/20 0.41
GRIN2A Q12879 2/20 0.41
GRIN2B Q13224 2/20 0.41
GRIN2C Q14957 2/20 0.41
GRIN3A Q8TCU5 2/20 0.41
GRIK1 P39086 1/20 0.41
GRIK2 Q13002 1/20 0.41
GRIK3 Q13003 1/20 0.41
GRIK4 Q16099 1/20 0.41
GRIK5 Q16478 1/20 0.41
LMNA P02545 1/20 0.37
FLT1 P17948 1/20 0.36
FLT4 P35916 1/20 0.36
KDR P35968 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7645895 0.91 BCAT1 (0.39) CA12CA1CA2CA9
SCHEMBL7648020 0.86 GRIN1 (0.35) GRIN2DGRIN3BGRIA1GRIA2GRIA3
SCHEMBL7646348 0.86 PGR (0.39) LMNAPOLB
SCHEMBL7653443 0.86 CA9 (0.42) LMNASMN1; SMN2CA12CA1CA2
SCHEMBL7650908 0.85 GRIN2D (0.45) GRIN2DGRIN3BGRIA1GRIA2GRIA3
SCHEMBL7647210 0.83 GRIN2D (0.38) GRIN2DGRIN3BGRIA1GRIA2GRIA3
SCHEMBL7647190 0.83 GRIN1 (0.35) GRIN2DGRIN3BGRIA1GRIA2GRIA3
SCHEMBL7648070 0.83 CA12 (0.33) GRIN2DGRIN3BGRIA1GRIA2GRIA3
SCHEMBL7652290 0.83 ALDH1A1 (0.41) L3MBTL1POLBSMN1; SMN2
SCHEMBL7647652 0.82 KDM4E (0.38) GRIN2DGRIN3BGRIA1GRIA2GRIA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6486143-B2 NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS LES LABORATOIRES SERVIER (FR) 2002-11-26 US disclosed
US-20010031746-A1 6-amino- or 6-hydrazino-sulphonyl-3-quinolynyl-phosphonic acid compounds LES LABORATOIRES SERVIER (FR) 2001-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010031746-A1 6-amino- or 6-hydrazino-sulphonyl-3-quinolynyl-phosphonic acid compounds CA6, P2RY6, FPR3 GRIN2D 1500/4885GRIN3B 919/4885GRIA1 889/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.