Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MPI | P34949 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | TACR3 | P29371 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7647401 | 0.90 | HTR6 (0.38) | HTR6MTNR1AMTNR1BALDH1A1KDM4E | |
| SCHEMBL7655581 | 0.88 | HTR6 (0.37) | HTR6MTNR1AMTNR1BALDH1A1KDM4E | |
| SCHEMBL7649355 | 0.87 | CHRNA7 (0.37) | HTR6MTNR1AMTNR1BALDH1A1KDM4E | |
| SCHEMBL7650707 | 0.85 | HTR6 (0.41) | HTR6MTNR1AMTNR1BALDH1A1KDM4E | |
| SCHEMBL8054347 | 0.82 | PRKCZ (0.41) | HTR6MTNR1AMTNR1BCYP1A2HTR2A | |
| SCHEMBL10676621 | 0.79 | MEN1 (0.48) | HTR6MTNR1AMTNR1BALDH1A1KDM4E | |
| SCHEMBL27550729 | 0.78 | MAPT (0.46) | MTNR1AMTNR1BALDH1A1KDM4EMAPT | |
| SCHEMBL10672207 | 0.78 | L3MBTL1 (0.48) | HTR6MTNR1AMTNR1BALDH1A1KDM4E | |
| SCHEMBL15345674 | 0.78 | HTR2A (0.48) | HTR6ALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL7364107 | 0.77 | TRPM4 (0.43) | ALDH1A1MAPTHPGDTDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492364-B1 | Triazolo and derivatives as chemokine inhibitors | TORAY INDUSTRIES, INC. (JP) | 2002-12-10 | — | — | US | disclosed |
| CN-1293674-A | Triazolo gerivatives and chemokine inhibitors containing the same as the active ingredient | TORAY INDUSTRIES (JP) | 2001-05-02 | — | — | CN | disclosed |
| EP-1067130-A1 | TRIAZOLO DERIVATIVES AND CHEMOKINE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2001-01-10 | — | — | EP | disclosed |