Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MPI | P34949 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | TACR3 | P29371 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.33 |
| ▸ | CHRNA10 | Q9GZZ6 | 2/20 | 0.33 |
| ▸ | CHRNA9 | Q9UGM1 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7655581 | 0.95 | HTR6 (0.37) | HTR6MTNR1AMTNR1BKDM4EMEN1 | |
| SCHEMBL7649355 | 0.94 | CHRNA7 (0.37) | HTR6MTNR1AMTNR1BKDM4EMEN1 | |
| SCHEMBL7649102 | 0.90 | HTR6 (0.40) | HTR6MTNR1AMTNR1BKDM4EMEN1 | |
| SCHEMBL7650707 | 0.82 | HTR6 (0.41) | HTR6MTNR1AMTNR1BKDM4EMEN1 | |
| SCHEMBL27550729 | 0.82 | MAPT (0.46) | MTNR1AMTNR1BKDM4EALDH1A1MAPT | |
| SCHEMBL8054347 | 0.79 | PRKCZ (0.41) | HTR6MTNR1AMTNR1BHTR2A | |
| SCHEMBL7654443 | 0.78 | CYP1A2 (0.48) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL7654463 | 0.78 | MTNR1A (0.37) | MTNR1AKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL10676621 | 0.77 | MEN1 (0.48) | HTR6MTNR1AMTNR1BKDM4EMEN1 | |
| SCHEMBL7648253 | 0.76 | LTA4H (0.36) | KDM4EMEN1MAPTKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492364-B1 | Triazolo and derivatives as chemokine inhibitors | TORAY INDUSTRIES, INC. (JP) | 2002-12-10 | — | — | US | disclosed |
| CN-1293674-A | Triazolo gerivatives and chemokine inhibitors containing the same as the active ingredient | TORAY INDUSTRIES (JP) | 2001-05-02 | — | — | CN | disclosed |
| EP-1067130-A1 | TRIAZOLO DERIVATIVES AND CHEMOKINE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2001-01-10 | — | — | EP | disclosed |