Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7070564 | 0.87 | LMNA (0.49) | LMNAMAPTGAAKMT2ANPSR1 | |
| SCHEMBL7655621 | 0.87 | LMNA (0.57) | LMNAMAPTGAADGAT1KMT2A | |
| SCHEMBL7076643 | 0.87 | LMNA (0.53) | LMNAMAPTKMT2ANPSR1POLB | |
| SCHEMBL7071584 | 0.86 | GAA (0.52) | LMNAMAPTGAADGAT1KMT2A | |
| SCHEMBL8075470 | 0.84 | LMNA (0.46) | LMNAMAPTGAAKMT2ANPSR1 | |
| SCHEMBL7654110 | 0.83 | LMNA (0.53) | LMNAMAPTGAADGAT1KMT2A | |
| SCHEMBL7070226 | 0.82 | THRB (0.54) | LMNAMAPTDGAT1KMT2APOLB | |
| SCHEMBL7076863 | 0.82 | LSS (0.49) | LMNAMAPTPOLB | |
| SCHEMBL7070015 | 0.82 | LMNA (0.57) | LMNAMAPTNPSR1 | |
| SCHEMBL7648189 | 0.81 | LMNA (0.53) | LMNAMAPTGAADGAT1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |