Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 6/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7648189 | 0.91 | LMNA (0.53) | LMNAMAPTGAASMN1; SMN2KMT2A | |
| SCHEMBL7071592 | 0.88 | LMNA (0.50) | LMNAMAPTGAASMN1; SMN2KMT2A | |
| SCHEMBL7075993 | 0.87 | ATM (0.66) | LMNAMAPTGAASMN1; SMN2KMT2A | |
| SCHEMBL7655621 | 0.86 | LMNA (0.57) | LMNAMAPTGAASMN1; SMN2KMT2A | |
| SCHEMBL7069977 | 0.84 | PKM (0.55) | LMNAGAASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL7649347 | 0.83 | LMNA (0.53) | LMNAMAPTGAAKMT2APKM | |
| SCHEMBL7652755 | 0.82 | MAPT (0.59) | LMNAMAPTGAAKMT2AALDH1A1 | |
| SCHEMBL7074028 | 0.82 | MAPT (0.62) | LMNAMAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL1660858 | 0.80 | MAPT (0.61) | LMNAMAPTGAASMN1; SMN2KMT2A | |
| SCHEMBL7074071 | 0.79 | KDM4E (0.56) | LMNAMAPTGAASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |