Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7655724 | 0.96 | KDM4E (0.46) | KDM4EMAPTALOX15SMN1; SMN2 | |
| SCHEMBL9421311 | 0.96 | KDM4E (0.41) | KDM4EMAPTALOX15SMN1; SMN2 | |
| Potassium Ion SCHEMBL11756064 | 0.79 | KDM4E (0.34) | KDM4EMAPTALOX15SMN1; SMN2 | |
| SCHEMBL17295990 | 0.77 | KDM4E (0.39) | KDM4EMAPTALOX15SMN1; SMN2 | |
| SCHEMBL897217 | 0.77 | TDP1 (0.39) | KDM4EALOX15 | |
| SCHEMBL8993258 | 0.73 | KDM4E (0.36) | KDM4EMAPTALOX15SMN1; SMN2 | |
| SCHEMBL18983977 | 0.72 | KDM4E (0.38) | KDM4EMAPTALOX15SMN1; SMN2 | |
| Potassium Ion SCHEMBL9421284 | 0.71 | CA1 (0.37) | KDM4EMAPTALOX15SMN1; SMN2 | |
| Potassium Ion SCHEMBL30410092 | 0.71 | KDM4E (0.36) | KDM4EMAPTALOX15SMN1; SMN2 | |
| SCHEMBL10631687 | 0.70 | KDM4E (0.31) | KDM4EMAPTALOX15SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6491824-B1 | ADDING EMULSION BREAKER TO SEPARATE WATER AND OIL; PRE-FILTRATION, CLARIFICATION | BJ SERVICES COMPANY | 2002-12-10 | — | — | US | claimed |
| US-6491824-B1 | ADDING EMULSION BREAKER TO SEPARATE WATER AND OIL; PRE-FILTRATION, CLARIFICATION | BJ SERVICES COMPANY | 2002-12-10 | — | — | US | disclosed |