Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NMUR2 | Q9GZQ4 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 6/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12207269 | 0.75 | KDM4E (0.43) | RAB9AKMT2AHSD17B10MEN1KDM4E | |
| SCHEMBL752464 | 0.74 | ALDH1A1 (0.52) | NPC1RAB9ANMUR2KMT2AMEN1 | |
| SCHEMBL765516 | 0.72 | MAPT (0.40) | NMUR2KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL755830 | 0.71 | MAPT (0.43) | NPC1RAB9ANMUR2KMT2ACYP3A4 | |
| SCHEMBL13351798 | 0.70 | NMUR2 (0.41) | NPC1RAB9ANMUR2KMT2ACYP3A4 | |
| SCHEMBL30224972 | 0.67 | CYP3A4 (0.54) | NMUR2KMT2ACYP3A4HSD17B10MEN1 | |
| SCHEMBL30807193 | 0.67 | CYP3A4 (0.77) | NPC1RAB9ANMUR2KMT2ACYP3A4 | |
| SCHEMBL752884 | 0.66 | KDM4E (0.65) | NMUR2KMT2ACYP3A4HSD17B10MEN1 | |
| SCHEMBL756396 | 0.64 | LMNA (0.56) | RAB9AKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL28637328 | 0.64 | CYP3A4 (0.47) | NMUR2KMT2ACYP3A4HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1422218-B1 | ANTIVIRAL AGENT | SHIONOGI & CO (JP) | 2012-03-21 | — | — | EP | disclosed |