SCHEMBL755830

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13351798	0.87	NMUR2 (0.41)	MAPTNPC1RAB9ANMUR2KMT2A
	SCHEMBL754426	0.82	KMT2A (0.43)	MAPTKMT2AALDH1A1POLBKDM4E
	SCHEMBL16925481	0.80	MAPT (0.40)	MAPTNMUR2KMT2AALDH1A1MAPK1
	SCHEMBL13255593	0.78	PARP1 (0.40)	NPC1RAB9AKMT2AALDH1A1POLB
	SCHEMBL752464	0.77	ALDH1A1 (0.52)	MAPTNPC1RAB9ANMUR2KMT2A
	SCHEMBL754937	0.76	ALDH1A1 (0.42)	MAPTNPC1RAB9AKMT2AALDH1A1
	SCHEMBL752919	0.75	POLB (0.37)	MAPTKMT2AALDH1A1POLBTP53
	SCHEMBL753088	0.74	POLB (0.38)	MAPTALDH1A1POLBLMNA
	SCHEMBL755446	0.74	TEAD4 (0.42)	MAPTKMT2AALDH1A1POLBKDM4E
	SCHEMBL755559	0.74	MMP3 (0.47)	NPC1RAB9AKMT2AALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.