Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 2/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7648253 | 0.91 | LTA4H (0.36) | LTA4HTSHRKMT2AKDM4EGLA | |
| SCHEMBL7646978 | 0.89 | LTA4H (0.35) | LTA4HTSHRKMT2AKDM4EGLA | |
| SCHEMBL7652971 | 0.88 | ESR1 (0.34) | LTA4HTSHRKMT2AKDM4EGLA | |
| SCHEMBL7654683 | 0.87 | LTA4H (0.41) | LTA4HTSHRKMT2AKDM4EGLA | |
| SCHEMBL25016073 | 0.80 | L3MBTL1 (0.44) | LTA4HTSHRKMT2AKDM4EGLA | |
| SCHEMBL15345467 | 0.80 | HTR2A (0.44) | LTA4HTSHRKMT2ATRPM8MEN1 | |
| SCHEMBL25016118 | 0.76 | LTA4H (0.38) | LTA4HTSHRKMT2AKDM4EGLA | |
| SCHEMBL7649102 | 0.75 | HTR6 (0.40) | KMT2AKDM4EMAPTMEN1TDP1 | |
| SCHEMBL7654726 | 0.74 | LTA4H (0.46) | LTA4HTSHRKMT2AKDM4EGLA | |
| SCHEMBL7364107 | 0.73 | TRPM4 (0.43) | TSHRMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492364-B1 | Triazolo and derivatives as chemokine inhibitors | TORAY INDUSTRIES, INC. (JP) | 2002-12-10 | — | — | US | disclosed |
| EP-1067130-A1 | TRIAZOLO DERIVATIVES AND CHEMOKINE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2001-01-10 | — | — | EP | disclosed |