Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.34 |
| ▸ | LTA4H | P09960 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7646978 | 0.99 | LTA4H (0.35) | ESR1ESR2LTA4HTSHRPGR | |
| SCHEMBL7648253 | 0.94 | LTA4H (0.36) | ESR1ESR2LTA4HTSHRPGR | |
| SCHEMBL7650776 | 0.88 | LTA4H (0.39) | LTA4HTSHRPGRKDM4EGLA | |
| SCHEMBL7654683 | 0.82 | LTA4H (0.41) | LTA4HTSHRPGRKDM4EGLA | |
| SCHEMBL7649355 | 0.78 | CHRNA7 (0.37) | KDM4EMAPTKMT2A | |
| SCHEMBL7655581 | 0.76 | HTR6 (0.37) | ESR1ESR2KDM4EMAPTKMT2A | |
| SCHEMBL7652962 | 0.76 | CYP1A2 (0.46) | MAPT | |
| SCHEMBL25016073 | 0.75 | L3MBTL1 (0.44) | LTA4HTSHRPGRKDM4EGLA | |
| SCHEMBL15345467 | 0.75 | HTR2A (0.44) | LTA4HTSHRKMT2ATRPM8 | |
| SCHEMBL7763131 | 0.74 | NQO2 (0.47) | KDM4EGLAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492364-B1 | Triazolo and derivatives as chemokine inhibitors | TORAY INDUSTRIES, INC. (JP) | 2002-12-10 | — | — | US | disclosed |
| EP-1067130-A1 | TRIAZOLO DERIVATIVES AND CHEMOKINE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2001-01-10 | — | — | EP | disclosed |