Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | CTSG | P08311 | 1/20 | 0.37 |
| ▸ | CMA1 | P23946 | 1/20 | 0.37 |
| ▸ | CTRC | Q99895 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7658829 | 0.95 | EP300 (0.53) | EP300LMNAABCB11PTGS1MEN1 | |
| SCHEMBL7660452 | 0.90 | CCKBR (0.39) | EP300LMNAABCB11PTGS1MAPT | |
| SCHEMBL7839682 | 0.85 | LMNA (0.36) | EP300LMNAABCB11PTGS1MEN1 | |
| SCHEMBL7655852 | 0.82 | EP300 (0.46) | EP300LMNAMEN1KMT2AHPGD | |
| SCHEMBL7658228 | 0.82 | EP300 (0.50) | EP300MEN1KMT2AHTTF2 | |
| SCHEMBL7657008 | 0.80 | EP300 (0.68) | EP300LMNAMEN1KMT2AHPGD | |
| SCHEMBL7665570 | 0.80 | MAPT (0.39) | MEN1KMT2AHPGDMAPTHTT | |
| SCHEMBL6841466 | 0.75 | ALDH1A1 (0.53) | EP300LMNAMEN1KMT2AHPGD | |
| SCHEMBL7665537 | 0.72 | EP300 (0.53) | EP300MEN1KMT2AMAPTHTT | |
| SCHEMBL11375405 | 0.69 | EP300 (0.69) | EP300MEN1KMT2AMAPTF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6498164-B1 | SUCH AS 1,3-DIBENZYL-5-(PHENYL- OR 2-THIENYL-ACETYL)BARBI-TURIC ACID; MALIGNANT HYPERCALCEMIA, OSTEOLYTIC DISEASES SUCH AS PAGET'S DISEASE, OSTEOPOROSIS, ARTICULAR RHEUMATISM OCCURRING IN KNEES, SHOULDERS, JOINTS | AVENTIS PHARMA S.A. (FR) | 2002-12-24 | — | — | US | disclosed |