Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7650490 | 0.85 | MAPK11 (0.40) | KDM4EALDH1A1ADORA3CDK4CCND1 | |
| SCHEMBL7656709 | 0.80 | NPC1 (0.48) | MAPTKDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL7654423 | 0.80 | ALDH1A1 (0.47) | MAPTKDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL7656767 | 0.79 | GAA (0.54) | KDM4EALDH1A1TP53HTTGAA | |
| SCHEMBL7660378 | 0.77 | ALDH1A1 (0.53) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL7650664 | 0.74 | ADORA3 (0.44) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL7652334 | 0.74 | HCAR1 (0.39) | ADORA3TNKSTNKS2CYP1A1CYP1B1 | |
| SCHEMBL7652867 | 0.74 | ALDH1A1 (0.48) | MAPTKDM4EKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL7654345 | 0.74 | GAA (0.40) | MAPTKDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL7649039 | 0.73 | PPP1CA (0.51) | KDM4EALDH1A1TP53HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492407-B2 | NEUROPROTECTIVE ACTIVITY | BOEHRINGER IMGELHEIM PHARMA KG (DE) | 2002-12-10 | — | — | US | disclosed |