Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7604958 | 0.76 | EPHX1 (0.43) | ALOX5BCHEACHEIDO1ALDH1A1 | |
| SCHEMBL7651581 | 0.68 | ALDH1A1 (0.44) | ALOX5IDO1ALDH1A1EPHX1SMN1; SMN2 | |
| SCHEMBL6122244 | 0.61 | TSHR (0.65) | ALOX5BCHEACHEALDH1A1F2RL1 | |
| SCHEMBL6121660 | 0.61 | TSHR (0.65) | ALOX5BCHEACHEALDH1A1F2RL1 | |
| SCHEMBL31329297 | 0.60 | ALOX5 (0.82) | ALOX5BCHEACHEALDH1A1CYP3A4 | |
| SCHEMBL6122069 | 0.60 | TSHR (0.63) | ALOX5BCHEACHEALDH1A1F2RL1 | |
| SCHEMBL10691859 | 0.60 | ALOX5 (1.00) | ALOX5BCHEACHEALDH1A1F2RL1 | |
| SCHEMBL6121985 | 0.60 | TSHR (0.63) | ALOX5BCHEACHEALDH1A1F2RL1 | |
| SCHEMBL9973241 | 0.60 | IDO1 (0.44) | ALOX5IDO1ALDH1A1EPHX1F2RL1 | |
| SCHEMBL10823756 | 0.59 | IDO1 (0.59) | ALOX5IDO1ALDH1A1EPHX1F2RL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212096-A2 | DRUG CONJUGATES AND METHODS OF DESIGNING THE SAME | Brenner, Sydney (US) | 2002-06-12 | — | — | EP | disclosed |
| WO-2001013958-A2 | DRUG CONJUGATES AND METHODS OF DESIGNING THE SAME | BRENNER SYDNEY (US) | 2001-03-01 | — | — | WO | disclosed |