Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7604900 | 0.80 | EPHX1 (0.45) | EPHX1ALOX5IDO1L3MBTL1GAA | |
| SCHEMBL7651583 | 0.76 | ALOX5 (0.41) | EPHX1ALOX5BCHEACHEIDO1 | |
| SCHEMBL8932479 | 0.72 | TAAR1 (0.50) | EPHX1BCHEACHEIDO1ALDH1A1 | |
| SCHEMBL7651581 | 0.69 | ALDH1A1 (0.44) | EPHX1ALOX5IDO1GAAALDH1A1 | |
| SCHEMBL7088679 | 0.65 | SLC6A4 (0.58) | EPHX1BCHEACHEIDO1L3MBTL1 | |
| SCHEMBL6121660 | 0.64 | TSHR (0.65) | ALOX5BCHEACHEL3MBTL1ALDH1A1 | |
| SCHEMBL5971492 | 0.64 | SLC6A4 (0.53) | EPHX1BCHEACHEIDO1ALDH1A1 | |
| SCHEMBL7881281 | 0.64 | SLC6A4 (0.52) | EPHX1BCHEACHEIDO1ALDH1A1 | |
| SCHEMBL6122069 | 0.63 | TSHR (0.63) | ALOX5BCHEACHEL3MBTL1ALDH1A1 | |
| SCHEMBL7346371 | 0.63 | L3MBTL1 (0.62) | EPHX1IDO1L3MBTL1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212096-A2 | DRUG CONJUGATES AND METHODS OF DESIGNING THE SAME | Brenner, Sydney (US) | 2002-06-12 | — | — | EP | disclosed |
| WO-2001013958-A2 | DRUG CONJUGATES AND METHODS OF DESIGNING THE SAME | BRENNER SYDNEY (US) | 2001-03-01 | — | — | WO | disclosed |