Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6221210 | 1.00 | MAOA (0.53) | MAOAMAOBALDH1A1HPGDMTNR1A | |
| SCHEMBL2237332 | 1.00 | MAOA (0.53) | MAOAMAOBALDH1A1HPGDMTNR1A | |
| SCHEMBL7445938 | 0.86 | ALDH1A1 (0.49) | MAOAMAOBALDH1A1HPGDMTNR1A | |
| SCHEMBL10977541 | 0.85 | KIF11 (0.55) | MAOAMAOBMTNR1AMTNR1BRAB9A | |
| SCHEMBL2951317 | 0.85 | KIF11 (0.55) | MAOAMAOBMTNR1AMTNR1BRAB9A | |
| Hydrochloric Acid SCHEMBL3610043 | 0.83 | KIF11 (0.53) | MAOAMAOBMTNR1AMTNR1BRAB9A | |
| Hydrochloric Acid SCHEMBL3610046 | 0.83 | KIF11 (0.53) | MAOAMAOBMTNR1AMTNR1BRAB9A | |
| SCHEMBL6840772 | 0.82 | ALDH1A1 (0.47) | MAOAMAOBALDH1A1MTNR1AMTNR1B | |
| SCHEMBL13659834 | 0.81 | MAOA (0.58) | MAOAMAOBALDH1A1MTNR1AMTNR1B | |
| SCHEMBL342512 | 0.80 | MAOA (0.57) | MAOAMAOBMTNR1AMTNR1BKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358978-B1 | FOR THERAPY AND PROPHYLAXIS OF RHEUMATOID ARTHRITIS (IN THE CASE OF INFLAMMATION), OSTEOARTHRITIS, ASTHMA, CARDIAC INFARCT, ALZHEIMER'S DISEASE, OR ATHEROSCLEROSIS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-03-19 | — | — | US | disclosed |
| CN-1030229-A | Butenoic acid amides, their salts, pharmaceutical compositions containing them and process for preparing them | RICHTER GEDEON VEGYESZET (HU) | 1989-01-11 | — | — | CN | disclosed |