Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7651607 | 1.00 | MAOA (0.53) | MAOAMAOBALDH1A1HPGDMTNR1A | |
| SCHEMBL6221210 | 1.00 | MAOA (0.53) | MAOAMAOBALDH1A1HPGDMTNR1A | |
| SCHEMBL7445938 | 0.86 | ALDH1A1 (0.49) | MAOAMAOBALDH1A1HPGDMTNR1A | |
| SCHEMBL10977541 | 0.85 | KIF11 (0.55) | MAOAMAOBMTNR1AMTNR1BRAB9A | |
| SCHEMBL2951317 | 0.85 | KIF11 (0.55) | MAOAMAOBMTNR1AMTNR1BRAB9A | |
| Hydrochloric Acid SCHEMBL3610043 | 0.83 | KIF11 (0.53) | MAOAMAOBMTNR1AMTNR1BRAB9A | |
| Hydrochloric Acid SCHEMBL3610046 | 0.83 | KIF11 (0.53) | MAOAMAOBMTNR1AMTNR1BRAB9A | |
| SCHEMBL6840772 | 0.82 | ALDH1A1 (0.47) | MAOAMAOBALDH1A1MTNR1AMTNR1B | |
| SCHEMBL13659834 | 0.81 | MAOA (0.58) | MAOAMAOBALDH1A1MTNR1AMTNR1B | |
| SCHEMBL342512 | 0.80 | MAOA (0.57) | MAOAMAOBMTNR1AMTNR1BKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200231532-A1 | Supported Metal Catalysts | JOHNSON MATTHEY PLC (GB) | 2020-07-23 | — | — | US | claimed |
| US-20180099923-A1 | Supported Metal Catalysts | JOHNSON MATTHEY PLC (GB) | 2018-04-12 | — | — | US | claimed |
| EP-2536500-B1 | SUPPORTED METAL CATALYSTS | JOHNSON MATTHEY PLC (GB) | 2016-12-07 | — | — | EP | claimed |
| US-20130072722-A1 | SUPPORTED METAL CATALYSTS | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2013-03-21 | — | — | US | claimed |
| EP-2536500-A1 | SUPPORTED METAL CATALYSTS | Johnson Matthey PLC (GB) | 2012-12-26 | — | — | EP | claimed |
| WO-2011101679-A1 | SUPPORTED METAL CATALYSTS | JOHNSON MATTHEY PLC (GB) | 2011-08-25 | — | — | WO | claimed |
| US-20200231532-A1 | Supported Metal Catalysts | JOHNSON MATTHEY PLC (GB) | 2020-07-23 | — | — | US | disclosed |
| US-20180099923-A1 | Supported Metal Catalysts | JOHNSON MATTHEY PLC (GB) | 2018-04-12 | — | — | US | disclosed |
| EP-2536500-B1 | SUPPORTED METAL CATALYSTS | JOHNSON MATTHEY PLC (GB) | 2016-12-07 | — | — | EP | disclosed |
| US-20130072722-A1 | SUPPORTED METAL CATALYSTS | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2013-03-21 | — | — | US | disclosed |
| EP-2536500-A1 | SUPPORTED METAL CATALYSTS | Johnson Matthey PLC (GB) | 2012-12-26 | — | — | EP | disclosed |
| WO-2011101679-A1 | SUPPORTED METAL CATALYSTS | JOHNSON MATTHEY PLC (GB) | 2011-08-25 | — | — | WO | disclosed |
| US-4766110-A | INHIBITS ANGIOTENSIN CONVERTING ENZYME, HYPOTENSIVE AGENTS | RYAN JAMES W (US) | 1988-08-23 | — | — | US | disclosed |
| EP-0073143-A2 | Novel complex amido and imido derivatives of carboxyalkyl peptides and thioethers and ethers of peptides | Ryan, James Walter (US) | 1983-03-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130072722-A1 | SUPPORTED METAL CATALYSTS | SOD1, HNMT, SOD3 | MAOA 40/4885MAOB 157/4885ALDH1A1 1906/4885 |
| US-20200231532-A1 | Supported Metal Catalysts | SOD1, HNMT, SOD3 | MAOA 40/4885MAOB 157/4885ALDH1A1 1906/4885 |
| US-20180099923-A1 | Supported Metal Catalysts | SOD1, HNMT, SOD3 | MAOA 40/4885MAOB 157/4885ALDH1A1 1906/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.