Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.49 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.49 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7074868 | 0.89 | KMT2A (0.52) | KMT2AMEN1MAPK1ALDH1A1MAPT | |
| SCHEMBL7071435 | 0.85 | KMT2A (0.64) | KMT2AMEN1MAPK1ALDH1A1MAPT | |
| SCHEMBL7074218 | 0.81 | ALDH1A1 (0.67) | MAPK1ALDH1A1MAPTPKMGAA | |
| SCHEMBL7071685 | 0.81 | KMT2A (0.49) | KMT2AMEN1MAPK1ALDH1A1MAPT | |
| SCHEMBL7654095 | 0.80 | GAA (0.53) | KMT2AMEN1MAPK1ALDH1A1MAPT | |
| SCHEMBL7070571 | 0.80 | GAA (0.58) | KMT2AALDH1A1NPC1PKMGAA | |
| SCHEMBL7074851 | 0.80 | GAA (0.63) | KMT2AALDH1A1NPC1PKMGAA | |
| SCHEMBL7073684 | 0.79 | F2 (0.55) | KMT2AMEN1MAPK1ALDH1A1MAPT | |
| SCHEMBL7074652 | 0.78 | F2 (0.54) | KMT2AMEN1ALDH1A1MAPTPKM | |
| SCHEMBL7069339 | 0.78 | CNR1 (0.55) | KMT2AALDH1A1PKMGAAF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |