Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | HPN | P05981 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7071435 | 0.85 | KMT2A (0.64) | GAAALDH1A1MAPTNPC1KMT2A | |
| SCHEMBL7074841 | 0.84 | KMT2A (0.45) | GAAALDH1A1MAPTNPC1KMT2A | |
| SCHEMBL7651893 | 0.80 | KMT2A (0.53) | GAAALDH1A1MAPTNPC1KMT2A | |
| SCHEMBL7073684 | 0.79 | F2 (0.55) | GAAALDH1A1MAPTNPC1KMT2A | |
| SCHEMBL7074868 | 0.79 | KMT2A (0.52) | GAAALDH1A1MAPTNPC1KMT2A | |
| SCHEMBL7649390 | 0.78 | KMT2A (0.56) | GAAALDH1A1MAPTNPC1KMT2A | |
| SCHEMBL7652755 | 0.78 | MAPT (0.59) | GAAALDH1A1MAPTNPC1KMT2A | |
| SCHEMBL7649409 | 0.77 | F10 (0.60) | GAAALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL7649509 | 0.76 | GAA (0.61) | GAAALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL7654506 | 0.76 | GAA (0.53) | GAAMAPTKMT2AMEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |