Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | PLG | P00747 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.51 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.51 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7651893 | 0.89 | KMT2A (0.53) | KMT2AMEN1PKMMAPK1F2 | |
| SCHEMBL7071685 | 0.89 | KMT2A (0.49) | KMT2AMEN1PKMMAPK1F2 | |
| SCHEMBL7074639 | 0.84 | ALDH1A1 (0.55) | PKMF2PLGPRSS1TPSAB1 | |
| SCHEMBL7071435 | 0.83 | KMT2A (0.64) | KMT2AMEN1MAPK1ALDH1A1MAPT | |
| SCHEMBL7076655 | 0.81 | ALDH1A1 (0.55) | KMT2APKMF2PLGPRSS1 | |
| SCHEMBL7075075 | 0.79 | CNR1 (0.56) | KMT2AMEN1PKMF2PLG | |
| SCHEMBL7654095 | 0.79 | GAA (0.53) | KMT2AMEN1MAPK1ALDH1A1MAPT | |
| SCHEMBL7073684 | 0.78 | F2 (0.55) | KMT2AMEN1MAPK1F2PRSS1 | |
| SCHEMBL7073594 | 0.78 | PKM (0.72) | KMT2AMEN1PKMF2PLG | |
| SCHEMBL7076872 | 0.77 | NAAA (0.55) | KMT2APKMMAPK1F2PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |