Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7658278 | 0.92 | MAPT (0.52) | ADORA3MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL7657325 | 0.92 | ADORA3 (0.54) | ADORA3ADORA2BADORA2AMAPTHIF1A | |
| SCHEMBL7652943 | 0.88 | RPA1 (0.52) | ADORA3ADORA2AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7650590 | 0.86 | KDM4E (0.49) | ADORA2AMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL7649140 | 0.86 | TP53 (0.58) | ADORA3ADORA2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL7682175 | 0.86 | ALDH1A1 (0.55) | ADORA3MEN1KMT2AMAPTNPC1 | |
| SCHEMBL7650966 | 0.85 | ADORA3 (0.45) | ADORA3ADORA2AKMT2AMAPTALDH1A1 | |
| SCHEMBL7656264 | 0.84 | ALDH1A1 (0.61) | ADORA3ADORA2ASMN1; SMN2MAPTRAB9A | |
| SCHEMBL7656778 | 0.83 | HIF1A (0.49) | ADORA3ADORA2AMAPTHIF1AALDH1A1 | |
| SCHEMBL7659590 | 0.82 | PPP1CA (0.50) | ADORA3MAPTCYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492407-B2 | NEUROPROTECTIVE ACTIVITY | BOEHRINGER IMGELHEIM PHARMA KG (DE) | 2002-12-10 | — | — | US | disclosed |