Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | GFER | P55789 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | RORC | P51449 | 1/20 | 0.53 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7651061 | 0.83 | RAB9A (0.60) | MAPTGFERNPSR1POLBALDH1A1 | |
| SCHEMBL9845804 | 0.83 | ALDH1A1 (0.75) | MAPTPOLBALDH1A1TDP1L3MBTL1 | |
| SCHEMBL362394 | 0.80 | ALDH1A1 (0.66) | NPSR1ALDH1A1L3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL1355592 | 0.78 | CYP1A2 (0.59) | ALDH1A1CYP1A2CYP3A4CYP2C9PDE3B | |
| SCHEMBL9845802 | 0.77 | MEN1 (0.67) | MAPTPOLBALDH1A1TDP1L3MBTL1 | |
| SCHEMBL23963234 | 0.77 | HTR1A (0.59) | ALDH1A1CYP1A2CYP3A4CYP2C9RORC | |
| SCHEMBL13766306 | 0.77 | SMN1; SMN2 (0.58) | MAPTPOLBL3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL11629241 | 0.75 | NAMPT (0.74) | MAPTNPSR1POLBALDH1A1TRPV1 | |
| SCHEMBL12409531 | 0.74 | CYP1A2 (0.66) | MAPTPOLBALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL2389201 | 0.74 | ROCK2 (0.62) | POLBALDH1A1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407120-B1 | ADMINISTERING PYRIDINYLACETAMIDE OR PHENYLACETAMIDE DERIVATIVE TO TREAT CARDIOVASCULAR, EATING, SEXUAL, BRAIN, NERVOUS SYSTEM, GASTROINTESTINAL, UROGENITAL, PSYCHOLOGICAL, AND RESPIRATORY SYSTEM DISORDERS | PFIZER INC. | 2002-06-18 | — | — | US | disclosed |