Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 16/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 16/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 16/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7653508 | 0.90 | ITGAV (0.43) | ITGAVITGB3ITGA2B | |
| SCHEMBL7655212 | 0.88 | ITGB3 (0.65) | ITGAVITGB3ITGA2B | |
| SCHEMBL7658786 | 0.85 | ITGAV (0.60) | ITGAVITGB3ITGA2B | |
| SCHEMBL7652796 | 0.84 | PKM (0.38) | ITGAVITGB3ITGA2B | |
| SCHEMBL7653324 | 0.82 | ITGB3 (0.46) | ITGAVITGB3ITGA2B | |
| SCHEMBL7653514 | 0.79 | LMNA (0.35) | ITGAVITGB3ITGA2B | |
| SCHEMBL7655239 | 0.79 | KDM4E (0.44) | ITGAVITGB3ITGA2B | |
| SCHEMBL7651403 | 0.79 | ITGB3 (0.57) | ITGAVITGB3ITGA2B | |
| SCHEMBL7651419 | 0.79 | ITGB3 (0.59) | ITGAVITGB3ITGA2B | |
| SCHEMBL7658557 | 0.78 | ITGB3 (0.65) | ITGAVITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6451800-B1 | Phenylpiperazine derivatives as integrin αvβ3 antagonists | MEIJI SEIKA KAISHA, LTD. (JP) | 2002-09-17 | — | — | US | claimed |
| EP-1057818-A1 | PHENYLPIPERAZINE DERIVATIVES AS INTEGRIN ALPHAvBETA3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2000-12-06 | — | — | EP | claimed |
| US-6451800-B1 | Phenylpiperazine derivatives as integrin αvβ3 antagonists | MEIJI SEIKA KAISHA, LTD. (JP) | 2002-09-17 | — | — | US | disclosed |
| EP-1057818-A1 | PHENYLPIPERAZINE DERIVATIVES AS INTEGRIN ALPHAvBETA3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2000-12-06 | — | — | EP | disclosed |