Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.43 |
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4379375 | 0.87 | TSHR (0.50) | ALDH1A1GAALMNACYP2D6CYP2C19 | |
| SCHEMBL22115811 | 0.84 | CES2 (0.59) | ALDH1A1GAALMNACYP2D6CYP2C19 | |
| SCHEMBL22619 | 0.84 | CES2 (0.59) | ALDH1A1GAALMNACYP2D6CYP2C19 | |
| SCHEMBL7649397 | 0.83 | TDP1 (0.53) | ALDH1A1GAALMNACES2CES1 | |
| SCHEMBL27660831 | 0.83 | ALDH1A1 (0.56) | ALDH1A1GAALMNACYP2D6CYP2C19 | |
| SCHEMBL11203207 | 0.82 | ALDH1A1 (0.53) | ALDH1A1GAALMNACYP2D6CYP2C19 | |
| SCHEMBL7648805 | 0.81 | ADRB2 (0.49) | ALDH1A1LMNACES2CES1SMN1; SMN2 | |
| SCHEMBL2430960 | 0.81 | LMNA (0.68) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL7648706 | 0.80 | CA1 (0.58) | CES2CES1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7648909 | 0.80 | CHRM2 (0.48) | ALDH1A1GAACYP2C19L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6491903-B1 | NARROW MOLECULAR WEIGHT DISTRIBUTION SHELL-CORE POLYMERS HAVING HYDROPHILIC, CROSSLINKED PERMEABLE SHELLS AND HYDROPHOBIC CORES, USED FOR REDUCING BLOOD CHOLESTEROL AND BILE ACID UPTAKE IN INTERSTINES; DRUG DELIVERY | WASHINGTON UNIVERSITY | 2002-12-10 | — | — | US | disclosed |
| US-6383500-B1 | Particles comprising amphiphilic copolymers, having a crosslinked shell domain and an interior core domain, useful for pharmaceutical and other applications | WASHINGTON UNIVERSITY | 2002-05-07 | — | — | US | disclosed |