Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7662890 | 0.85 | KMT2A (0.32) | KMT2AMAPTAOC3MEN1ALDH1A1 | |
| SCHEMBL7105240 | 0.82 | — | — | |
| SCHEMBL7662704 | 0.72 | GRIN2D (0.39) | — | |
| SCHEMBL7660598 | 0.72 | CHRNB2 (0.32) | KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL7103722 | 0.72 | — | — | |
| SCHEMBL7655038 | 0.71 | PDCD1 (0.44) | KMT2AMAPTMEN1LMNAKDM4E | |
| SCHEMBL7653615 | 0.70 | PDCD1 (0.40) | KMT2AMAPTMEN1ALDH1A1LMNA | |
| SCHEMBL7652140 | 0.69 | PNP (0.39) | KMT2AMAPTMEN1ALDH1A1LMNA | |
| SCHEMBL22973717 | 0.68 | PGK1 (0.36) | — | |
| SCHEMBL31418395 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399613-B1 | N,N'-BIS(2-HYDROXYETHYL)PYRAZINE-2,5- OR -2,6-DICARBOXAMIDE; DIABETES | AVENTIS PHARMA S.A. (FR) | 2002-06-04 | — | — | US | claimed |
| US-6399613-B1 | N,N'-BIS(2-HYDROXYETHYL)PYRAZINE-2,5- OR -2,6-DICARBOXAMIDE; DIABETES | AVENTIS PHARMA S.A. (FR) | 2002-06-04 | — | — | US | disclosed |