Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.55 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15533244 | 0.93 | HTR2A (0.62) | HTR2AHTR2CTAAR1 | |
| SCHEMBL7637946 | 0.87 | HTR2A (0.49) | HTR2AGPR55MAPT | |
| SCHEMBL15540748 | 0.85 | HTR2A (0.45) | HTR2AGPR55 | |
| SCHEMBL7630243 | 0.85 | HTR2A (0.48) | HTR2AGPR55MAPTHTR2C | |
| SCHEMBL7636001 | 0.85 | POLB (0.53) | HTR2AGPR55 | |
| SCHEMBL15532149 | 0.82 | HTR2A (0.51) | HTR2AHTR2C | |
| SCHEMBL1539339 | 0.80 | SLC5A2 (0.53) | HTR2A | |
| SCHEMBL3766451 | 0.79 | ALDH1A1 (0.46) | GPR55MAPT | |
| SCHEMBL3891823 | 0.79 | LMNA (0.55) | MAPT | |
| SCHEMBL12185684 | 0.79 | LTA4H (0.50) | GPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6455549-B1 | ANTIEPILEPTIC, ANTIISCHEMIC, AND ANTIMIGRAINE AGENTS; CALCIUM OVELOAD SUPPRESSANTS | SUNTORY LIMITED (JP) | 2002-09-24 | — | — | US | disclosed |