SCHEMBL7653133

SCHEMBL7653133

NC[C@H](NS(=O)(=O)c1ccc(F)cc1)C(=O)OC(=O)C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 1/20 0.44
SLC1A2 P43004 1/20 0.44
SLC1A1 P43005 1/20 0.44
MMP2 P08253 5/20 0.42
MMP9 P14780 5/20 0.42
MMP1 P03956 3/20 0.42
MMP13 P45452 3/20 0.42
CA1 P00915 3/20 0.42
CA2 P00918 3/20 0.42
MMP8 P22894 2/20 0.42
MMP3 P08254 2/20 0.41
MMP7 P09237 3/20 0.40
MMP10 P09238 1/20 0.39
MMP12 P39900 1/20 0.39
MMP14 P50281 1/20 0.39
EGFR P00533 1/20 0.38
ERBB2 P04626 1/20 0.38
PSMB8 P28062 1/20 0.37
PSMB5 P28074 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL7653125 0.81 SLC1A3 (0.53) SLC1A3SLC1A2SLC1A1MMP2MMP9
SCHEMBL7656972 0.80 MMP7 (0.55) SLC1A3SLC1A2MMP2MMP9MMP1
SCHEMBL7661320 0.80 ALDH1A1 (0.42) MMP2MMP1MMP13MMP3MEN1
SCHEMBL7375346 0.78 SLC1A3 (0.60) SLC1A3SLC1A2SLC1A1MMP2MMP9
SCHEMBL7654081 0.77 SLC1A3 (0.45) SLC1A3SLC1A2SLC1A1MEN1LMNA
SCHEMBL4958594 0.75 MMP2 (0.57) MMP2MMP9MMP1MMP13MMP8
SCHEMBL7699209 0.75 F2 (0.42) MMP2MMP13MMP14L3MBTL1F2
SCHEMBL7661156 0.73
SCHEMBL15012377 0.71 MMP3 (0.35) SLC1A3SLC1A2SLC1A1MMP2MMP9
SCHEMBL7661122 0.71 NR3C2 (0.40) MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6335337-B1 ANTICOAGULANTS LABORATOIRE L. LAFON (FR) 2002-01-01 US disclosed