Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 11/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 11/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | GRK2 | P25098 | 1/20 | 0.40 |
| ▸ | GRK5 | P34947 | 1/20 | 0.40 |
| ▸ | GRK3 | P35626 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | DGAT2 | Q96PD7 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7658025 | 0.92 | MTNR1A (0.53) | MTNR1AMTNR1BGRK2GRK5GRK3 | |
| SCHEMBL7377866 | 0.88 | MTNR1A (0.48) | MTNR1AMTNR1BGRK2GRK5GRK3 | |
| SCHEMBL7411156 | 0.85 | MTNR1A (0.52) | MTNR1AMTNR1BPDE4D | |
| SCHEMBL7658223 | 0.85 | MTNR1A (0.52) | MTNR1AMTNR1BPDE4D | |
| SCHEMBL7408317 | 0.85 | MTNR1A (0.51) | MTNR1AMTNR1BGRK2GRK5GRK3 | |
| SCHEMBL7655897 | 0.84 | MTNR1A (0.45) | MTNR1AMTNR1B | |
| SCHEMBL7656731 | 0.84 | MTNR1A (0.43) | MTNR1AMTNR1BGRK2GRK5GRK3 | |
| SCHEMBL7655794 | 0.76 | ALDH1A1 (0.45) | MTNR1AMTNR1BPDE4D | |
| SCHEMBL7653083 | 0.74 | MEN1 (0.53) | GRK2GRK5GRK3PDE4D | |
| SCHEMBL12192806 | 0.72 | FFAR1 (0.61) | MTNR1AMTNR1BFFAR1TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358973-B1 | FOR THERAPY OF ALLERGIC OR INFLAMMATORY DISEASE | ZAMBON GROUP S.P.A. (IT) | 2002-03-19 | — | — | US | disclosed |