Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.42 |
| ▸ | PRKG1 | Q13976 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | UGCG | Q16739 | 1/20 | 0.41 |
| ▸ | GRK2 | P25098 | 1/20 | 0.40 |
| ▸ | GRK5 | P34947 | 1/20 | 0.40 |
| ▸ | GRK3 | P35626 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7655897 | 0.80 | MTNR1A (0.45) | POLBROCK2PRKG1 | |
| SCHEMBL7408317 | 0.76 | MTNR1A (0.51) | SMN1; SMN2PDE4DGRK2GRK5GRK3 | |
| SCHEMBL7655794 | 0.76 | ALDH1A1 (0.45) | ALDH1A1ROCK2SMN1; SMN2PDE4D | |
| SCHEMBL7656731 | 0.76 | MTNR1A (0.43) | MEN1KMT2AALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL7658025 | 0.76 | MTNR1A (0.53) | SMN1; SMN2PDE4DGRK2GRK5GRK3 | |
| SCHEMBL7653203 | 0.74 | MTNR1A (0.51) | PDE4DGRK2GRK5GRK3 | |
| SCHEMBL7377866 | 0.74 | MTNR1A (0.48) | MEN1KMT2AROCK2SMN1; SMN2PDE4D | |
| SCHEMBL7411156 | 0.69 | MTNR1A (0.52) | MEN1KMT2APDE4D | |
| SCHEMBL7658223 | 0.69 | MTNR1A (0.52) | MEN1KMT2APDE4D | |
| SCHEMBL7100679 | 0.67 | POLB (0.55) | MEN1KMT2AALDH1A1MAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376429-B1 | CONTROLLING WEEDS | HOECHST SCHERING AGREVO GMBH (DE) | 2002-04-23 | — | — | US | claimed |
| US-6358973-B1 | FOR THERAPY OF ALLERGIC OR INFLAMMATORY DISEASE | ZAMBON GROUP S.P.A. (IT) | 2002-03-19 | — | — | US | disclosed |