Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7411156 | 1.00 | MTNR1A (0.52) | MTNR1AMTNR1BKMT2APDE4DP2RX7 | |
| SCHEMBL7653203 | 0.85 | MTNR1A (0.51) | MTNR1AMTNR1BPDE4D | |
| SCHEMBL7658025 | 0.83 | MTNR1A (0.53) | MTNR1AMTNR1BPDE4DP2RX7CA1 | |
| SCHEMBL7408317 | 0.82 | MTNR1A (0.51) | MTNR1AMTNR1BPDE4DBCHE | |
| SCHEMBL7377866 | 0.82 | MTNR1A (0.48) | MTNR1AMTNR1BKMT2APDE4DP2RX7 | |
| SCHEMBL7655794 | 0.82 | ALDH1A1 (0.45) | MTNR1AMTNR1BPDE4DRAB9AL3MBTL1 | |
| SCHEMBL7655897 | 0.78 | MTNR1A (0.45) | MTNR1AMTNR1BP2RX7 | |
| SCHEMBL7656731 | 0.78 | MTNR1A (0.43) | MTNR1AMTNR1BKMT2APDE4DMEN1 | |
| SCHEMBL7405335 | 0.71 | CASR (0.47) | MTNR1AMTNR1BKMT2AL3MBTL1 | |
| SCHEMBL7413751 | 0.71 | CASR (0.47) | MTNR1AMTNR1BKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358973-B1 | FOR THERAPY OF ALLERGIC OR INFLAMMATORY DISEASE | ZAMBON GROUP S.P.A. (IT) | 2002-03-19 | — | — | US | disclosed |