Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 8/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GRK2 | P25098 | 1/20 | 0.41 |
| ▸ | GRK5 | P34947 | 1/20 | 0.41 |
| ▸ | GRK3 | P35626 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | DGAT2 | Q96PD7 | 2/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7408317 | 0.86 | MTNR1A (0.51) | MTNR1AMTNR1BSMN1; SMN2GRK2GRK5 | |
| SCHEMBL7377866 | 0.86 | MTNR1A (0.48) | MTNR1AMTNR1BSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7658025 | 0.85 | MTNR1A (0.53) | MTNR1AMTNR1BSMN1; SMN2GRK2GRK5 | |
| SCHEMBL7653203 | 0.84 | MTNR1A (0.51) | MTNR1AMTNR1BGRK2GRK5GRK3 | |
| SCHEMBL7655897 | 0.80 | MTNR1A (0.45) | MTNR1AMTNR1B | |
| SCHEMBL7411156 | 0.78 | MTNR1A (0.52) | MTNR1AMTNR1BMEN1KMT2APDE4D | |
| SCHEMBL7658223 | 0.78 | MTNR1A (0.52) | MTNR1AMTNR1BMEN1KMT2APDE4D | |
| SCHEMBL7653083 | 0.76 | MEN1 (0.53) | SMN1; SMN2MEN1KMT2AGRK2GRK5 | |
| SCHEMBL7655794 | 0.76 | ALDH1A1 (0.45) | MTNR1AMTNR1BSMN1; SMN2ALDH1A1PDE4D | |
| SCHEMBL18403140 | 0.66 | AOC3 (0.50) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358973-B1 | FOR THERAPY OF ALLERGIC OR INFLAMMATORY DISEASE | ZAMBON GROUP S.P.A. (IT) | 2002-03-19 | — | — | US | disclosed |