Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2386760 | 0.74 | TDP1 (0.52) | LMNASMN1; SMN2TRPA1GAAALDH1A1 | |
| SCHEMBL2388601 | 0.74 | TDP1 (0.52) | LMNASMN1; SMN2TRPA1GAAALDH1A1 | |
| SCHEMBL10977217 | 0.74 | LMNA (0.40) | LMNASMN1; SMN2GAAMAPTHTT | |
| SCHEMBL5010102 | 0.73 | KMT2A (0.50) | GAAMAPTHTTALDH1A1MEN1 | |
| SCHEMBL5011920 | 0.73 | ALDH1A1 (0.44) | LMNASMN1; SMN2GAAMAPTMCL1 | |
| SCHEMBL5011802 | 0.71 | MEN1 (0.46) | LMNAMAPTHTTMCL1ALDH1A1 | |
| SCHEMBL3903241 | 0.69 | HTT (0.34) | GAAMAPTHTTALDH1A1MEN1 | |
| SCHEMBL11115341 | 0.69 | HTT (0.51) | LMNASMN1; SMN2GAAMAPTHTT | |
| SCHEMBL11289142 | 0.68 | GRK6 (0.34) | LMNAMAPTHTTMCL1ALDH1A1 | |
| SCHEMBL13576324 | 0.68 | MAPT (0.51) | LMNASMN1; SMN2GAAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6361913-B1 | ELECTROGRAPHY IMAGES, SUBSTRATES WITH CHARGE GENERATING LAYER AND CHARGE TRANSPORT LAYER, OVERCOATING AND HYDROXY TRIPHENYL METHANE | XEROX CORPORATION | 2002-03-26 | — | — | US | claimed |