Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.56 |
| ▸ | WNT3A | P56704 | 8/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.49 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.49 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12303054 | 0.81 | WNT3A (0.82) | WNT3A | |
| SCHEMBL22777899 | 0.80 | KDM4E (0.60) | TRPV1NPC1RAB9AMAPTKDM4E | |
| SCHEMBL21286267 | 0.77 | RAB9A (0.68) | WNT3ANPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL22777877 | 0.76 | RECQL (0.51) | AOC3WNT3ATRPV1NPC1RAB9A | |
| SCHEMBL7651621 | 0.76 | KCNQ2 (0.47) | TRPV1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL24645772 | 0.76 | MAPT (0.67) | TRPV1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL7652890 | 0.76 | KCNQ2 (0.55) | TRPV1SMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL4969527 | 0.76 | KCNQ3 (0.60) | TRPV1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL22777906 | 0.76 | TRPV1 (0.53) | AOC3WNT3ATRPV1NPC1RAB9A | |
| SCHEMBL22791539 | 0.76 | TRPV1 (0.53) | AOC3TRPV1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407120-B1 | ADMINISTERING PYRIDINYLACETAMIDE OR PHENYLACETAMIDE DERIVATIVE TO TREAT CARDIOVASCULAR, EATING, SEXUAL, BRAIN, NERVOUS SYSTEM, GASTROINTESTINAL, UROGENITAL, PSYCHOLOGICAL, AND RESPIRATORY SYSTEM DISORDERS | PFIZER INC. | 2002-06-18 | — | — | US | disclosed |