Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 14/20 | 0.45 |
| ▸ | CFTR | P13569 | 4/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7806936 | 0.91 | CFTR (0.49) | CAMK2DCFTRUSP2ALDH1A1CYP1A2 | |
| Trifluoroacetic Acid SCHEMBL7658458 | 0.87 | CAMK2D (0.42) | CAMK2DPIM1USP2ALDH1A1CYP1A2 | |
| Acetic Acid SCHEMBL7658116 | 0.84 | CAMK2D (0.49) | CAMK2DPIM1USP2ALDH1A1CYP1A2 | |
| Trifluoroacetic Acid SCHEMBL7815291 | 0.83 | CAMK2D (0.46) | CAMK2DPIM1USP2ALDH1A1CYP1A2 | |
| Trifluoroacetic Acid SCHEMBL7817667 | 0.82 | CAMK2D (0.44) | CAMK2DPIM1 | |
| Trifluoroacetic Acid SCHEMBL8516825 | 0.82 | CA12 (0.40) | CAMK2DPIM1USP2ALDH1A1CYP1A2 | |
| Trifluoroacetic Acid SCHEMBL7818314 | 0.81 | CAMK2D (0.48) | CAMK2DPIM1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL7815071 | 0.80 | ALDH1A1 (0.49) | CAMK2DPIM1USP2ALDH1A1CYP1A2 | |
| Trifluoroacetic Acid SCHEMBL7814735 | 0.80 | PDE4B (0.44) | CAMK2DCFTRPIM1USP2ALDH1A1 | |
| SCHEMBL7663803 | 0.80 | CAMK2D (0.52) | CAMK2DCFTRUSP2ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6458792-B1 | MEDICAMENT FOR THE TREATMENT OF INFLAMMATORY, IMMUNOLOGICAL, BRONCHOPULMONARY, CARDIOVASCULAR, ONCOLOGICAL OR CNS-DEGENERATIVE DISORDERS. | ASTRAZENECA AB (SE) | 2002-10-01 | — | — | US | claimed |
| US-6458792-B1 | MEDICAMENT FOR THE TREATMENT OF INFLAMMATORY, IMMUNOLOGICAL, BRONCHOPULMONARY, CARDIOVASCULAR, ONCOLOGICAL OR CNS-DEGENERATIVE DISORDERS. | ASTRAZENECA AB (SE) | 2002-10-01 | — | — | US | disclosed |