Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | CAMK2D | Q13557 | 11/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7815291 | 0.90 | CAMK2D (0.46) | CAMK2DPIM1USP2ALDH1A1CYP1A2 | |
| Trifluoroacetic Acid SCHEMBL7817667 | 0.89 | CAMK2D (0.44) | CAMK2DPIM1 | |
| Trifluoroacetic Acid SCHEMBL7806936 | 0.89 | CFTR (0.49) | CAMK2DCFTRUSP2ALDH1A1CYP1A2 | |
| Trifluoroacetic Acid SCHEMBL7815071 | 0.88 | ALDH1A1 (0.49) | CAMK2DPIM1USP2ALDH1A1CYP1A2 | |
| Trifluoroacetic Acid SCHEMBL7818314 | 0.86 | CAMK2D (0.48) | CAMK2DPIM1ALDH1A1MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL7817211 | 0.85 | MAPT (0.43) | CAMK2DPIM1USP2ALDH1A1CYP1A2 | |
| Trifluoroacetic Acid SCHEMBL7807656 | 0.84 | MAPT (0.43) | CAMK2DPIM1USP2ALDH1A1CYP1A2 | |
| Trifluoroacetic Acid SCHEMBL8516338 | 0.83 | ALDH1A1 (0.45) | CAMK2DUSP2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7806891 | 0.83 | CAMK2D (0.53) | CAMK2DPIM1USP2ALDH1A1CYP1A2 | |
| Trifluoroacetic Acid SCHEMBL7814551 | 0.83 | USP2 (0.53) | CAMK2DPIM1USP2ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010025043-A1 | New pharmaceutical active compounds | ASTRA AKTIEBOLAG, A SWEDEN CORPORATION | 2001-09-27 | — | — | US | disclosed |
| US-6271231-B1 | Pharmaceutically active compounds | ASTRA AKTIEBOLAG (SE) | 2001-08-07 | — | — | US | disclosed |
| EP-0929551-A1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | Astra Aktiebolag (publ) (SE) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998013368-A1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRA AKTIEBOLAG (PUBL) (SE) | 1998-04-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010025043-A1 | New pharmaceutical active compounds | CSNK1A1, CSNK1G1, CSNK2A1 | PDE4B 342/4885PDE4D 302/4885CAMK2D 338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.