Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CAMK2D | Q13557 | 5/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 4/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7815291 | 0.94 | CAMK2D (0.46) | ALDH1A1CYP2C9CYP2C19CYP1A2CAMK2D | |
| Trifluoroacetic Acid SCHEMBL8516338 | 0.90 | ALDH1A1 (0.45) | ALDH1A1KDM4EHTTCYP2C9CYP2C19 | |
| Trifluoroacetic Acid SCHEMBL7817667 | 0.89 | CAMK2D (0.44) | KDM4ECAMK2DPIM1 | |
| Trifluoroacetic Acid SCHEMBL7806936 | 0.89 | CFTR (0.49) | ALDH1A1CYP1A2CAMK2DUSP2 | |
| Trifluoroacetic Acid SCHEMBL7814551 | 0.88 | USP2 (0.53) | ALDH1A1KDM4EHTTCYP2C9CYP2C19 | |
| Trifluoroacetic Acid SCHEMBL7818314 | 0.88 | CAMK2D (0.48) | ALDH1A1KDM4EHTTRAB9ACAMK2D | |
| Trifluoroacetic Acid SCHEMBL7814735 | 0.88 | PDE4B (0.44) | ALDH1A1CYP2C9CYP2C19CYP1A2NPC1 | |
| Trifluoroacetic Acid SCHEMBL8365255 | 0.88 | MEN1 (0.42) | ALDH1A1KDM4EHTTCYP2C9CYP2C19 | |
| Trifluoroacetic Acid SCHEMBL7817211 | 0.87 | MAPT (0.43) | ALDH1A1CYP2C9CYP2C19CYP1A2CAMK2D | |
| SCHEMBL7806891 | 0.87 | CAMK2D (0.53) | ALDH1A1CYP2C9CYP2C19CYP1A2CAMK2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010025043-A1 | New pharmaceutical active compounds | ASTRA AKTIEBOLAG, A SWEDEN CORPORATION | 2001-09-27 | — | — | US | disclosed |
| US-6271231-B1 | Pharmaceutically active compounds | ASTRA AKTIEBOLAG (SE) | 2001-08-07 | — | — | US | disclosed |
| EP-0929551-A1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | Astra Aktiebolag (publ) (SE) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998013368-A1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRA AKTIEBOLAG (PUBL) (SE) | 1998-04-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010025043-A1 | New pharmaceutical active compounds | CSNK1A1, CSNK1G1, CSNK2A1 | ALDH1A1 2487/4885KDM4E 1621/4885HTT 4078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.