Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.60 |
| ▸ | DRD4 | P21917 | 5/20 | 0.47 |
| ▸ | DRD2 | P14416 | 4/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CCR2 | P41597 | 1/20 | 0.44 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6977509 | 0.85 | FAAH (0.51) | FAAHDRD4DRD2SCN9AMCHR1 | |
| SCHEMBL8045499 | 0.78 | FAAH (0.50) | FAAH | |
| SCHEMBL6978579 | 0.77 | LMNA (0.45) | FAAHHTR7 | |
| SCHEMBL19614234 | 0.77 | DRD4 (0.70) | DRD4DRD2MCHR1POLB | |
| SCHEMBL17961749 | 0.77 | DRD4 (0.70) | DRD4DRD2MCHR1POLB | |
| SCHEMBL20183285 | 0.77 | DRD4 (0.70) | DRD4DRD2MCHR1POLB | |
| Hydrochloric Acid SCHEMBL6979904 | 0.77 | FAAH (0.49) | FAAH | |
| Hydrochloric Acid SCHEMBL8045138 | 0.77 | FAAH (0.49) | FAAH | |
| SCHEMBL8046807 | 0.77 | FAAH (0.41) | FAAH | |
| Oxalic Acid SCHEMBL1624809 | 0.75 | DRD4 (0.67) | DRD4DRD2MCHR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372736-B1 | ENZYME INHIBITORS | PFIZER INC | 2002-04-16 | — | — | US | disclosed |