Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 10/20 | 0.41 |
| ▸ | BCL2 | P10415 | 2/20 | 0.37 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 3/20 | 0.35 |
| ▸ | CCR4 | P51679 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7654968 | 0.77 | FAAH (0.60) | FAAH | |
| SCHEMBL6977509 | 0.70 | FAAH (0.51) | FAAH | |
| SCHEMBL6978579 | 0.70 | LMNA (0.45) | FAAHACKR3CCR4 | |
| SCHEMBL8045499 | 0.64 | FAAH (0.50) | FAAH | |
| SCHEMBL8046739 | 0.64 | TACR1 (0.35) | SMYD3 | |
| SCHEMBL8043737 | 0.64 | SMYD3 (0.42) | SMYD3 | |
| SCHEMBL8043736 | 0.64 | SMYD3 (0.42) | SMYD3 | |
| Hydrochloric Acid SCHEMBL6979904 | 0.63 | FAAH (0.49) | FAAH | |
| Hydrochloric Acid SCHEMBL8045138 | 0.63 | FAAH (0.49) | FAAH | |
| SCHEMBL23507491 | 0.62 | FAAH (0.60) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121280-A | Azabicyclic rotomase inhibitors | PFIZER INC. (US) | 2000-09-19 | — | — | US | disclosed |
| EP-0947506-A1 | 2-Aza-bicyclo[2.2.1]heptane derivatives and their use as rotamase inhibitors | Pfizer Products Inc. (US) | 1999-10-06 | — | — | EP | disclosed |