Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.44 |
| ▸ | CTSB | P07858 | 2/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.43 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7659603 | 0.89 | SIRT2 (0.45) | SIRT2SIRT1SIRT3KDM4EALDH1A1 | |
| SCHEMBL7662205 | 0.89 | SIRT2 (0.53) | SIRT2SIRT1SIRT3KDM4EALDH1A1 | |
| SCHEMBL7656191 | 0.86 | CFTR (0.47) | KDM4EALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL7659665 | 0.85 | GRM2 (0.54) | KDM4EALDH1A1HPGDGAAMAPT | |
| SCHEMBL7658391 | 0.84 | MAPT (0.45) | KDM4EALDH1A1HPGDGAAMAPT | |
| SCHEMBL7655647 | 0.82 | MAPT (0.51) | KDM4EALDH1A1HPGDGAAMAPT | |
| SCHEMBL7651397 | 0.78 | POLB (0.55) | KDM4EALDH1A1HPGDGAAMAPT | |
| SCHEMBL7659132 | 0.78 | KMT2A (0.62) | KDM4EALDH1A1MAPTSMN1; SMN2POLB | |
| SCHEMBL7655836 | 0.78 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDGAAMAPT | |
| SCHEMBL7655128 | 0.77 | RAB9A (0.52) | MAPTTP53SMN1; SMN2POLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340704-B1 | TREATING NERVE DISEASE OR BONE/JOINT DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-0975621-A1 | CELL DIFFERENTIATION INDUCING AMIDE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998049155-A1 | CELL DIFFERENTIATION INDUCING AMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-11-05 | — | — | WO | disclosed |