Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 12/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7656191 | 0.90 | CFTR (0.47) | GRM2KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL7658391 | 0.87 | MAPT (0.45) | GRM2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL7657898 | 0.85 | SIRT2 (0.44) | GRM2KDM4EALDH1A1TP53GAA | |
| SCHEMBL7655647 | 0.83 | MAPT (0.51) | KDM4EALDH1A1TP53GAAHPGD | |
| SCHEMBL7659425 | 0.81 | PLAU (0.44) | GRM2KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL7659132 | 0.81 | KMT2A (0.62) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7651397 | 0.79 | POLB (0.55) | GRM2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL7655836 | 0.79 | ALDH1A1 (0.50) | KDM4EALDH1A1GAAHPGDMEN1 | |
| SCHEMBL7655128 | 0.78 | RAB9A (0.52) | GRM2TP53MEN1KMT2AMAPT | |
| SCHEMBL7656725 | 0.76 | NR4A2 (0.45) | KDM4EALDH1A1HPGDKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340704-B1 | TREATING NERVE DISEASE OR BONE/JOINT DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-0975621-A1 | CELL DIFFERENTIATION INDUCING AMIDE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998049155-A1 | CELL DIFFERENTIATION INDUCING AMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-11-05 | — | — | WO | disclosed |