Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.41 |
| ▸ | DHFR | P00374 | 2/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | VNN1 | O95497 | 1/20 | 0.37 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6751413 | 0.91 | PLAU (0.47) | MRGPRX4PLAUCYP4F2CYP4A11LOXL2 | |
| SCHEMBL7656101 | 0.86 | PLAU (0.42) | MRGPRX4PLAUCYP4F2CYP4A11LOXL2 | |
| SCHEMBL6749963 | 0.83 | CYP4F2 (0.48) | MRGPRX4PLAUCYP4F2CYP4A11LOXL2 | |
| SCHEMBL6753784 | 0.83 | LOXL2 (0.53) | MRGPRX4PLAUCYP4F2CYP4A11LOXL2 | |
| SCHEMBL7663246 | 0.81 | MRGPRX4 (0.48) | MRGPRX4PLAULOXL2KAT6AMEN1 | |
| SCHEMBL7717556 | 0.80 | PLAU (0.50) | MRGPRX4PLAUEGLN1KAT6AXDH | |
| SCHEMBL7714047 | 0.79 | MRGPRX4 (0.51) | MRGPRX4PLAUEGLN1KAT6A | |
| SCHEMBL7662548 | 0.79 | MRGPRX4 (0.51) | MRGPRX4PLAUKAT6AMEN1KMT2A | |
| SCHEMBL7665912 | 0.79 | MRGPRX4 (0.48) | MRGPRX4PLAU | |
| SCHEMBL7822720 | 0.78 | PLAU (0.61) | MRGPRX4PLAULOXL2KAT6AXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6348478-B1 | BLOOD COAGULATION FACTORS AND ANTICOAGULANTS | TEIJIN LIMITED (JP) | 2002-02-19 | — | — | US | disclosed |
| EP-1043311-A1 | BIPHENYLAMIDINE DERIVATIVES | TEIJIN LIMITED (JP) | 2000-10-11 | — | — | EP | disclosed |