Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | USP2 | O75604 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6751413 | 0.88 | PLAU (0.47) | PLAUMRGPRX4KAT6AEGLN1CYP4F2 | |
| SCHEMBL7656098 | 0.86 | MRGPRX4 (0.45) | PLAUMRGPRX4KAT6AMEN1KMT2A | |
| SCHEMBL6753784 | 0.82 | LOXL2 (0.53) | PLAUMRGPRX4KAT6AEGLN1CYP4F2 | |
| SCHEMBL6749963 | 0.82 | CYP4F2 (0.48) | PLAUMRGPRX4KAT6AEGLN1CYP4F2 | |
| SCHEMBL7663246 | 0.81 | MRGPRX4 (0.48) | PLAUMRGPRX4KAT6AMEN1KMT2A | |
| SCHEMBL7662548 | 0.81 | MRGPRX4 (0.51) | PLAUMRGPRX4KAT6AMEN1KMT2A | |
| SCHEMBL7717556 | 0.79 | PLAU (0.50) | PLAUMRGPRX4KAT6AEGLN1FNTA | |
| SCHEMBL7714047 | 0.78 | MRGPRX4 (0.51) | PLAUMRGPRX4KAT6AEGLN1 | |
| SCHEMBL7665912 | 0.78 | MRGPRX4 (0.48) | PLAUMRGPRX4ALDH1A1LMNAMMP13 | |
| SCHEMBL7822720 | 0.77 | PLAU (0.61) | PLAUMRGPRX4KAT6ALOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6348478-B1 | BLOOD COAGULATION FACTORS AND ANTICOAGULANTS | TEIJIN LIMITED (JP) | 2002-02-19 | — | — | US | disclosed |
| EP-1043311-A1 | BIPHENYLAMIDINE DERIVATIVES | TEIJIN LIMITED (JP) | 2000-10-11 | — | — | EP | disclosed |