Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7657267 | 0.70 | — | — | |
| SCHEMBL11229667 | 0.70 | LMNA (0.41) | OPRM1OPRL1LMNANPSR1GSK3A | |
| SCHEMBL9800228 | 0.64 | ALDH1A1 (0.35) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL7663878 | 0.63 | GAA (0.43) | SMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL11492801 | 0.61 | TSHR (0.35) | TSHRNPSR1 | |
| SCHEMBL3287190 | 0.61 | MAPK1 (0.38) | ALDH1A1OPRM1OPRL1LMNANPSR1 | |
| SCHEMBL8444083 | 0.61 | DPP4 (0.37) | ALDH1A1TSHROPRM1OPRL1GSK3A | |
| SCHEMBL2230464 | 0.61 | POLB (0.37) | ALDH1A1TSHRLMNACYP2C9CYP2C19 | |
| SCHEMBL4681766 | 0.61 | HTT (0.43) | SMN1; SMN2ALDH1A1LMNAGSK3AGSK3B | |
| SCHEMBL2991774 | 0.61 | HTT (0.43) | SMN1; SMN2ALDH1A1LMNAGSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407228-B1 | MIXING ISOCYANATE WITH VINYL ETHER; CYCLIZATION | JAPAN AS REPRESENTED BY DIRECTOR GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2002-06-18 | — | — | US | disclosed |