Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.65 |
| ▸ | DRD4 | P21917 | 5/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.49 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19614234 | 0.85 | DRD4 (0.70) | SIGMAR1DRD4DRD2 | |
| SCHEMBL17961749 | 0.85 | DRD4 (0.70) | SIGMAR1DRD4DRD2 | |
| SCHEMBL20183285 | 0.85 | DRD4 (0.70) | SIGMAR1DRD4DRD2 | |
| SCHEMBL6968971 | 0.83 | NPY5R (0.57) | SIGMAR1DRD4CHRM2CHRM1CHRM3 | |
| Oxalic Acid SCHEMBL1624809 | 0.83 | DRD4 (0.67) | SIGMAR1DRD4DRD2 | |
| SCHEMBL23507310 | 0.82 | CHRNB2 (0.55) | SIGMAR1DRD4CHRM2CHRM1CHRM3 | |
| SCHEMBL239998 | 0.82 | DRD2 (0.67) | SIGMAR1DRD4ALDH1A1DRD2 | |
| SCHEMBL239997 | 0.82 | DRD2 (0.67) | SIGMAR1DRD4ALDH1A1DRD2 | |
| SCHEMBL21061654 | 0.81 | ALDH1A1 (0.65) | SIGMAR1ALDH1A1MAPTHTTKDM4E | |
| SCHEMBL21061907 | 0.79 | ALDH1A1 (0.60) | SIGMAR1ALDH1A1MAPTHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372736-B1 | ENZYME INHIBITORS | PFIZER INC | 2002-04-16 | — | — | US | disclosed |