Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.52 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6295507 | 0.75 | MEN1 (1.00) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL860065 | 0.73 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL29446470 | 0.72 | NPC1 (1.00) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL31337729 | 0.70 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL10347428 | 0.70 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL31285917 | 0.70 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL30103233 | 0.69 | PDE7A (1.00) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL844588 | 0.69 | PDE7A (1.00) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL6796770 | 0.69 | CTSV (0.51) | ALDH1A1SMN1; SMN2KDM4EHPGDL3MBTL1 | |
| SCHEMBL3269756 | 0.69 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020082268-A1 | Therapeutic compounds for the treatment of asthma and allergy, and methods of use thereof | SEPRACOR INC. | 2002-06-27 | — | — | US | disclosed |
| WO-2001070737-A2 | THERAPEUTIC HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF ASTHMA AND ALLERGY AND USE THEREOF | SEPRACOR, INC. (US) | 2001-09-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020082268-A1 | Therapeutic compounds for the treatment of asthma and allergy, and methods of use thereof | LTC4S, LTA4H, HRH2 | ALDH1A1 417/4885MEN1 3193/4885KMT2A 2409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.