Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC25A5 | P05141 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CCKBR | P32239 | 1/20 | 0.31 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7658136 | 0.88 | SLC25A5 (0.42) | SLC25A5ALDH1A1MAPTCCKBRSORT1 | |
| SCHEMBL7660452 | 0.83 | CCKBR (0.39) | ALDH1A1MAPTCCKBR | |
| SCHEMBL7658228 | 0.80 | EP300 (0.50) | SLC25A5ALDH1A1GAA | |
| SCHEMBL7664138 | 0.75 | EP300 (0.53) | SLC25A5ALDH1A1CCKBRGAA | |
| SCHEMBL7833467 | 0.71 | SLC25A5 (0.39) | SLC25A5ALDH1A1CCKBRSORT1GAA | |
| SCHEMBL7665537 | 0.65 | EP300 (0.53) | ALDH1A1MAPTCCKBRGAA | |
| SCHEMBL7651075 | 0.65 | EP300 (0.61) | SLC25A5ALDH1A1GAA | |
| SCHEMBL12729608 | 0.59 | SLC25A5 (0.37) | SLC25A5 | |
| SCHEMBL20686104 | 0.57 | ABCB11 (0.32) | — | |
| SCHEMBL13649105 | 0.57 | SLC25A5 (0.35) | SLC25A5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6498164-B1 | SUCH AS 1,3-DIBENZYL-5-(PHENYL- OR 2-THIENYL-ACETYL)BARBI-TURIC ACID; MALIGNANT HYPERCALCEMIA, OSTEOLYTIC DISEASES SUCH AS PAGET'S DISEASE, OSTEOPOROSIS, ARTICULAR RHEUMATISM OCCURRING IN KNEES, SHOULDERS, JOINTS | AVENTIS PHARMA S.A. (FR) | 2002-12-24 | — | — | US | disclosed |
| EP-1064269-A1 | BARBITURIC ACID DERIVATIVE AND PREVENTIVE AND THERAPEUTIC AGENT FOR BONE AND CARTILAGE CONTAINING THE SAME | Hoechst Marion Roussel (FR) | 2001-01-03 | — | — | EP | disclosed |
| WO-1999050252-A2 | BARBITURIC ACID DERIVATIVE AND PREVENTIVE AND THERAPEUTIC AGENT FOR BONE AND CARTILAGE CONTAINING THE SAME | HOECHST MARION ROUSSEL (FR) | 1999-10-07 | — | — | WO | disclosed |