Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC25A5 | P05141 | 1/20 | 0.39 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.35 |
| ▸ | CCKBR | P32239 | 3/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7658136 | 0.81 | SLC25A5 (0.42) | SLC25A5SORT1CCKBRDAOALDH1A1 | |
| SCHEMBL5438951 | 0.72 | GAA (0.35) | SORT1CCKBRDAOALDH1A1GAA | |
| SCHEMBL7656836 | 0.71 | SLC25A5 (0.35) | SLC25A5SORT1CCKBRALDH1A1GAA | |
| SCHEMBL7664138 | 0.70 | EP300 (0.53) | SLC25A5CCKBRALDH1A1GAAHTT | |
| SCHEMBL29414499 | 0.64 | SLC25A5 (0.44) | SLC25A5ALDH1A1HSD17B10LMNA | |
| SCHEMBL7833468 | 0.64 | LMNA (0.49) | SLC25A5HSD17B10LMNA | |
| SCHEMBL17841541 | 0.63 | HSD17B10 (0.38) | ALDH1A1GAAHSD17B10TSHRLMNA | |
| SCHEMBL6967195 | 0.62 | ALDH1A1 (0.43) | ALDH1A1GAAHSD17B10LMNA | |
| SCHEMBL7651075 | 0.61 | EP300 (0.61) | SLC25A5ALDH1A1GAAHTTMEN1 | |
| SCHEMBL1573209 | 0.60 | SLC25A5 (0.47) | SLC25A5ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1064269-A1 | BARBITURIC ACID DERIVATIVE AND PREVENTIVE AND THERAPEUTIC AGENT FOR BONE AND CARTILAGE CONTAINING THE SAME | Hoechst Marion Roussel (FR) | 2001-01-03 | — | — | EP | disclosed |
| WO-1999050252-A2 | BARBITURIC ACID DERIVATIVE AND PREVENTIVE AND THERAPEUTIC AGENT FOR BONE AND CARTILAGE CONTAINING THE SAME | HOECHST MARION ROUSSEL (FR) | 1999-10-07 | — | — | WO | disclosed |