Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC25A5 | P05141 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CCKBR | P32239 | 3/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7656836 | 0.88 | SLC25A5 (0.35) | SLC25A5ALDH1A1MAPTCCKBRSORT1 | |
| SCHEMBL7664138 | 0.85 | EP300 (0.53) | SLC25A5ALDH1A1CCKBRGAAMEN1 | |
| SCHEMBL7833467 | 0.81 | SLC25A5 (0.39) | SLC25A5ALDH1A1CCKBRSORT1GAA | |
| SCHEMBL7665537 | 0.74 | EP300 (0.53) | ALDH1A1MAPTCCKBRGAAMEN1 | |
| SCHEMBL7651075 | 0.74 | EP300 (0.61) | SLC25A5ALDH1A1GAAMEN1CYP2C19 | |
| SCHEMBL7660452 | 0.70 | CCKBR (0.39) | ALDH1A1MAPTCCKBRSMN1; SMN2 | |
| SCHEMBL3422159 | 0.65 | MEN1 (0.44) | ALDH1A1MAPTSORT1GAADAO | |
| SCHEMBL15041961 | 0.64 | SLC25A5 (0.37) | SLC25A5ALDH1A1MAPTSORT1DAO | |
| SCHEMBL7484676 | 0.63 | SORT1 (0.39) | ALDH1A1CCKBRSORT1DAOSMN1; SMN2 | |
| SCHEMBL23948519 | 0.63 | LMNA (0.41) | ALDH1A1CCKBRSORT1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6498164-B1 | SUCH AS 1,3-DIBENZYL-5-(PHENYL- OR 2-THIENYL-ACETYL)BARBI-TURIC ACID; MALIGNANT HYPERCALCEMIA, OSTEOLYTIC DISEASES SUCH AS PAGET'S DISEASE, OSTEOPOROSIS, ARTICULAR RHEUMATISM OCCURRING IN KNEES, SHOULDERS, JOINTS | AVENTIS PHARMA S.A. (FR) | 2002-12-24 | — | — | US | claimed |
| US-6498164-B1 | SUCH AS 1,3-DIBENZYL-5-(PHENYL- OR 2-THIENYL-ACETYL)BARBI-TURIC ACID; MALIGNANT HYPERCALCEMIA, OSTEOLYTIC DISEASES SUCH AS PAGET'S DISEASE, OSTEOPOROSIS, ARTICULAR RHEUMATISM OCCURRING IN KNEES, SHOULDERS, JOINTS | AVENTIS PHARMA S.A. (FR) | 2002-12-24 | — | — | US | disclosed |