SCHEMBL7685869

SCHEMBL7685869

CSNC(=O)N(C)Cc1ccc(Br)nc1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 2/20 0.38
MMP9 P14780 2/20 0.38
MMP8 P22894 2/20 0.38
MMP13 P45452 2/20 0.38
MTOR P42345 1/20 0.36
HDAC1 Q13547 2/20 0.34
NAMPT P43490 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
CA12 O43570 1/20 0.33
CA9 Q16790 1/20 0.33
LMNA P02545 1/20 0.33
ABCC1 P33527 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
CYP11B1 P15538 1/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7657367 0.83 ALDH1A1 (0.44) MTORNPC1RAB9A
SCHEMBL7658385 0.83 MMP2 (0.38) MMP2MMP9MMP8MMP13MTOR
SCHEMBL27316424 0.75 MMP2 (0.34) MMP2MMP9MMP8MMP13HDAC1
SCHEMBL7669950 0.75 KDM4E (0.38) NAMPTNPC1RAB9A
SCHEMBL7666494 0.75 RAB9A (0.57) MTORNPC1RAB9ACA12CA9
SCHEMBL7668250 0.73 MMP2 (0.33) MMP2MMP9MMP8MMP13CYP11B1
SCHEMBL7668247 0.73 MMP2 (0.33) MMP2MMP9MMP8MMP13CYP11B1
SCHEMBL7662165 0.72 SMN1; SMN2 (0.38) MMP2MMP9MMP8MMP13LMNA
SCHEMBL743701 0.71 CHRNB2 (0.47) MMP2MMP9MMP8MMP13CYP11B1
SCHEMBL30408607 0.71 CHRNB2 (0.47) MMP2MMP9MMP8MMP13CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6407248-B1 INSECTICIDES, MITICIDES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2002-06-18 US disclosed
US-6124297-A COMBATTING INSECTS OR MITES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2000-09-26 US disclosed
US-5935981-A INSECTICIDAL/MITICIDAL ACTIVITY TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1999-08-10 US disclosed
US-5849768-A α-unsaturated amines, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1998-12-15 US disclosed
EP-0529680-B1 Intermediates, their production and their use for preparing alpha-unsaturated amines TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1998-05-13 EP disclosed
EP-0302389-B1 Alpha-unsaturated amines, their production and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1993-12-22 EP disclosed
US-5214152-A Insecticides, miticides TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-05-25 US disclosed
EP-0529680-A2 Intermediates, their production and their use for preparing alpha-unsaturated amines TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-03-03 EP disclosed
US-5175301-A Insecticide, miticide, pesticide TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-12-29 US disclosed
EP-0509559-A2 Alpha-unsaturated amines, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-10-21 EP disclosed